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mutations presented The truth that, as described under, CLL therapy is based around the existence or absence of those mutations. The current consensus is that, apart from clonal mutations, subclonal mutations which has a variant allelic frequency ranging from five to 10% (and therefore down below the edge of detection by typical molecular strategies) is also documented, whereas Those people by using a variant allelic frequency reduce than five% shouldn't, but there's Substantially controversy close to these troubles and this recommendation could change Down the road.
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